{"id":185,"date":"2024-02-06T09:44:00","date_gmt":"2024-02-06T09:44:00","guid":{"rendered":"https:\/\/aoliutech.digitalnatives.cc\/?page_id=185"},"modified":"2024-12-30T18:56:35","modified_gmt":"2024-12-30T18:56:35","slug":"technologies","status":"publish","type":"page","link":"https:\/\/aoliutech.digitalnatives.cc\/zh\/technologies\/","title":{"rendered":"Technologies"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"185\" class=\"elementor elementor-185\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c1b5650 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c1b5650\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ef43aea\" data-id=\"ef43aea\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1e0d75b elementor-widget elementor-widget-heading\" data-id=\"1e0d75b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">novel technology in continuous flow chemistry<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-da50405 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"da50405\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t<div class=\"elementor-element elementor-element-39414cb e-con-full e-flex e-con e-parent\" data-id=\"39414cb\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-fe1cd52 e-flex e-con-boxed e-con e-child\" data-id=\"fe1cd52\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8614968 elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"8614968\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;slideInLeft&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">FLOW TECHNOLOGY<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b62f417 elementor-widget-divider--view-line elementor-invisible elementor-widget elementor-widget-divider\" data-id=\"b62f417\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;slideInLeft&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d395e98 elementor-widget elementor-widget-eael-adv-tabs\" data-id=\"d395e98\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"eael-adv-tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t        <div data-scroll-on-click=\"no\" data-scroll-speed=\"300\" id=\"eael-advance-tabs-d395e98\" class=\"eael-advance-tabs eael-tabs-vertical eael-tab-auto-active \" data-tabid=\"d395e98\">\n            <div class=\"eael-tabs-nav \">\n                <ul class=\"eael-tab-inline-icon\" role=\"tablist\">\n                                            <li id=\"sps-flow-synthesizer\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"sps-flow-synthesizer-tab\" aria-expanded=\"false\">\n                            \n                                                        \n                                                            <span class=\"eael-tab-title title-after-icon\" >SPS-FLOW SYNTHESIZER<\/span>                            \n                                                    <\/li>\n                                            <li id=\"kg-scale-flow-synthesis\" class=\"inactive eael-tab-item-trigger eael-tab-nav-item\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"kg-scale-flow-synthesis-tab\" aria-expanded=\"false\">\n                            \n                                                        \n                                                            <span class=\"eael-tab-title title-after-icon\" >KG-SCALE FLOW SYNTHESIS<\/span>                            \n                                                    <\/li>\n                    \n                                  <\/ul>\n            <\/div>\n            \n            <div class=\"eael-tabs-content\">\n\t\t        \n                    <div id=\"sps-flow-synthesizer-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"sps-flow-synthesizer-tab\">\n\t\t\t\t        <div class=\"main-container\">\n<div class=\"col-6\" style=\"width: auto\"><img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/Rectangle-17836-1.png\" \/><\/div>\n<div class=\"col-6\" style=\"width: auto\">\n<ul>\n \t<li>Automated synthesis of 5 molecules at one time<\/li>\n \t<li>Compact setup (a fume hood size)<\/li>\n \t<li>Only one offline purification<\/li>\n \t<li>Reduced time and cost<\/li>\n<\/ul>\n<img decoding=\"async\" class=\"process-img\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/image-338.png\" \/>\n\n<\/div>\n<\/div>\n<h4 class=\"inner-head\">SPS-Flow Synthesis<\/h4>\n<div class=\"main-container bg-grey\">\n<div class=\"col-6\"><img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/SPS-Flow-Synthesis.png\" \/><\/div>\n<div class=\"col-6\"><img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/SPS-Flow-Synthesis.gif\" \/><\/div>\n<\/div>\n<div class=\"main-container-2\">\n<h4 class=\"inner-head\">SPS-Flow Casestudy<\/h4>\n\u201cA six-step prexasertib synthesis was achieved in a remarkable 65% overall isolated yield with a final purity of &gt;99.9%. In addition, 23 prexasertib analogues were synthesized&#8230; These analogues display both early and late-stage diversification, showcasing the ability to readily alter any portion of a molecule to explore structure\u2013activity relationships.\u201d\n<p style=\"margin-bottom: 0px\">Mark S. Kerr &amp; Kevin P. Cole<\/p>\nSynthetic Molecule Design and Development, Eli Lilly and Company, Indianapolis, IN, USA.\n\n<a style=\"text-decoration: none\" href=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/SPS-Flow-Synthesis-of-Prexasertib.pdf\" target=\"_blank\" rel=\"noopener\">SPS-Flow Synthesis of Prexasertib <img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/pdf.png\" width=\"22\" \/><\/a>\n\n<a style=\"text-decoration: none\" href=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/Eli-Lilly-Review.pdf\" target=\"_blank\" rel=\"noopener\">Review <img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/pdf.png\" width=\"22\" \/><\/a>\n\n<\/div>                    <\/div>\n\t\t        \n                    <div id=\"kg-scale-flow-synthesis-tab\" class=\"clearfix eael-tab-content-item inactive\" data-title-link=\"kg-scale-flow-synthesis-tab\">\n\t\t\t\t        Our in-house reactor design for continuous flow coupled with photochemical module has enable novel transformation up to Kilogram\/day of production\n<div class=\"main-container\">\n<div class=\"col-6\" style=\"margin: 10px\"><img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/KG-SCALE-FLOW-SYNTHESIS-1.jpg\" \/><\/div>\n<div class=\"col-6\" style=\"margin: 10px\"><img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/KG-SCALE-FLOW-SYNTHESIS-2.gif\" \/><\/div>\n<\/div>                    <\/div>\n\t\t                    <\/div>\n        <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a31dc8 elementor-tabs-view-vertical elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-invisible elementor-widget elementor-widget-tabs\" data-id=\"3a31dc8\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;slideInUp&quot;}\" data-widget_type=\"tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-tabs\">\n\t\t\t<div class=\"elementor-tabs-wrapper\" role=\"tablist\" >\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-6101\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-6101\" aria-expanded=\"false\">SPS-Flow Synthesizer<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-6102\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-6102\" aria-expanded=\"false\">Kg-scale flow synthesis<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"elementor-tabs-content-wrapper\" role=\"tablist\" aria-orientation=\"vertical\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-6101\" aria-expanded=\"false\">SPS-Flow Synthesizer<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-6101\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-6101\" tabindex=\"0\" hidden=\"false\"><div class=\"main-container\">\n<div class=\"col-6\" style=\"width: auto;\"><img decoding=\"async\" src=\"https:\/\/aoliutech.digitalnatives.cc\/wp-content\/uploads\/2024\/02\/Rectangle-17836-1.png\" \/><\/div>\n<div class=\"col-6\" style=\"width: auto;\">\n<ul>\n \t<li>Automated synthesis of 5 molecules at one time<\/li>\n \t<li>Compact setup (a fume hood size)<\/li>\n \t<li>Only one offline purification<\/li>\n \t<li>Reduced time and cost<\/li>\n<\/ul>\n<img decoding=\"async\" class=\"process-img\" src=\"https:\/\/aoliutech.digitalnatives.cc\/wp-content\/uploads\/2024\/02\/image-338.png\" \/>\n\n<\/div>\n<\/div>\n<h4 class=\"inner-head\">SPS-Flow Synthesis<\/h4>\n<div class=\"main-container bg-grey\">\n<div class=\"col-6\"><img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/SPS-Flow-Synthesis.png\" \/><\/div>\n<div class=\"col-6\"><img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/SPS-Flow-Synthesis.gif\" \/><\/div>\n<\/div>\n<div class=\"main-container-2\">\n<h4 class=\"inner-head\">SPS-Flow Casestudy<\/h4>\n\u201cA six-step prexasertib synthesis was achieved in a remarkable 65% overall isolated yield with a final purity of &gt;99.9%. In addition, 23 prexasertib analogues were synthesized&#8230; These analogues display both early and late-stage diversification, showcasing the ability to readily alter any portion of a molecule to explore structure\u2013activity relationships.\u201d\n<p style=\"margin-bottom: 0px;\">Mark S. Kerr &amp; Kevin P. Cole<\/p>\nSynthetic Molecule Design and Development, Eli Lilly and Company, Indianapolis, IN, USA.\n\n<a style=\"text-decoration: none;\" href=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/SPS-Flow-Synthesis-of-Prexasertib.pdf\" target=\"_blank\" rel=\"noopener\">SPS-Flow Synthesis of Prexasertib <img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/pdf.png\" width=\"22\" \/><\/a>\n\n<a style=\"text-decoration: none;\" href=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/Eli-Lilly-Review.pdf\" target=\"_blank\" rel=\"noopener\">Review <img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/pdf.png\" width=\"22\" \/><\/a>\n\n<\/div><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-6102\" aria-expanded=\"false\">Kg-scale flow synthesis<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-6102\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-6102\" tabindex=\"0\" hidden=\"hidden\">Our in-house reactor design for continuous flow coupled with photochemical module has enable novel transformation up to Kilogram\/day of production\n<div class=\"main-container\">\n<div class=\"col-6\" style=\"margin: 10px;\"><img decoding=\"async\" style=\"height: 212px;\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/KG-SCALE-FLOW-SYNTHESIS-1.jpg\" \/><\/div>\n<div class=\"col-6\" style=\"margin: 10px;\"><img decoding=\"async\" src=\"https:\/\/aoliutech.com\/wp-content\/uploads\/2024\/02\/KG-SCALE-FLOW-SYNTHESIS-2.gif\" \/><\/div>\n<\/div><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d451dbb e-flex e-con-boxed e-con e-parent\" data-id=\"d451dbb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>novel technology in continuous flow chemistry FLOW TECH [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-185","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/aoliutech.digitalnatives.cc\/zh\/wp-json\/wp\/v2\/pages\/185","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/aoliutech.digitalnatives.cc\/zh\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/aoliutech.digitalnatives.cc\/zh\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/aoliutech.digitalnatives.cc\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/aoliutech.digitalnatives.cc\/zh\/wp-json\/wp\/v2\/comments?post=185"}],"version-history":[{"count":179,"href":"https:\/\/aoliutech.digitalnatives.cc\/zh\/wp-json\/wp\/v2\/pages\/185\/revisions"}],"predecessor-version":[{"id":1772,"href":"https:\/\/aoliutech.digitalnatives.cc\/zh\/wp-json\/wp\/v2\/pages\/185\/revisions\/1772"}],"wp:attachment":[{"href":"https:\/\/aoliutech.digitalnatives.cc\/zh\/wp-json\/wp\/v2\/media?parent=185"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}